False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases.
Identifieur interne : 000753 ( Main/Exploration ); précédent : 000752; suivant : 000754False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases.
Auteurs : Dasheng Li [République populaire de Chine] ; Dawei Wang [République populaire de Chine] ; Jianping Dong [République populaire de Chine] ; Nana Wang [République populaire de Chine] ; He Huang [République populaire de Chine] ; Haiwang Xu [République populaire de Chine] ; Chen Xia [République populaire de Chine]Source :
- Korean journal of radiology [ 2005-8330 ] ; 2020.
Descripteurs français
- KwdFr :
- MESH :
- imagerie diagnostique : Infections à coronavirus, Pneumopathie virale.
- virologie : Infections à coronavirus, Pneumopathie virale.
- Adulte, Faux négatifs, Humains, Mâle, Nourrisson, RT-PCR, Tomodensitométrie.
English descriptors
- KwdEn :
- Adult, Betacoronavirus (genetics), Betacoronavirus (isolation & purification), Coronavirus Infections (diagnostic imaging), Coronavirus Infections (virology), Deep Learning, False Negative Reactions, Humans, Infant, Male, Pneumonia, Viral (diagnostic imaging), Pneumonia, Viral (virology), Reverse Transcriptase Polymerase Chain Reaction, Tomography, X-Ray Computed.
- MESH :
- diagnostic imaging : Coronavirus Infections, Pneumonia, Viral.
- genetics : Betacoronavirus.
- isolation & purification : Betacoronavirus.
- virology : Coronavirus Infections, Pneumonia, Viral.
- Adult, Deep Learning, False Negative Reactions, Humans, Infant, Male, Reverse Transcriptase Polymerase Chain Reaction, Tomography, X-Ray Computed.
Abstract
The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. The nucleic acid test or genetic sequencing serves as the gold standard method for confirmation of infection, yet several recent studies have reported false-negative results of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). Here, we report two representative false-negative cases and discuss the supplementary role of clinical data with rRT-PCR, including laboratory examination results and computed tomography features. Coinfection with SARS-COV-2 and other viruses has been discussed as well.
DOI: 10.3348/kjr.2020.0146
PubMed: 32174053
Affiliations:
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diagnostique)</term><term>Pneumopathie virale (virologie)</term><term>RT-PCR</term><term>Tomodensitométrie</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Betacoronavirus</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Deep Learning</term><term>False Negative Reactions</term><term>Humans</term><term>Infant</term><term>Male</term><term>Reverse Transcriptase Polymerase Chain Reaction</term><term>Tomography, X-Ray Computed</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Faux négatifs</term><term>Humains</term><term>Mâle</term><term>Nourrisson</term><term>RT-PCR</term><term>Tomodensitométrie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. 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Coinfection with SARS-COV-2 and other viruses has been discussed as well.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Li, Dasheng" sort="Li, Dasheng" uniqKey="Li D" first="Dasheng" last="Li">Dasheng Li</name></noRegion><name sortKey="Dong, Jianping" sort="Dong, Jianping" uniqKey="Dong J" first="Jianping" last="Dong">Jianping Dong</name><name sortKey="Huang, He" sort="Huang, He" uniqKey="Huang H" first="He" last="Huang">He Huang</name><name sortKey="Wang, Dawei" sort="Wang, Dawei" uniqKey="Wang D" first="Dawei" last="Wang">Dawei Wang</name><name sortKey="Wang, Nana" sort="Wang, Nana" uniqKey="Wang N" first="Nana" last="Wang">Nana Wang</name><name sortKey="Xia, Chen" sort="Xia, Chen" uniqKey="Xia C" first="Chen" last="Xia">Chen Xia</name><name sortKey="Xu, Haiwang" sort="Xu, Haiwang" uniqKey="Xu H" first="Haiwang" last="Xu">Haiwang Xu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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